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FDA recently announced that a clinical trial evaluating the effects of doripenem (Doribax, Janssen) on the treatment of patients with ventilator-associated pneumonia was halted because of an increase in death rate and a poor clinical cure rate.

FDA and Seattle Genetics, which makes brentuximab vedotin (Adcetris), have updated the warning label on the company’s cancer drug after a second patient developed progressive multifocal leukoencephalopathy.

The Endocrine Society recently released new clinical practice guidelines recommending that all patients have their blood-glucose levels tested upon admission to the hospital, even if they haven’t been diagnosed with diabetes.

Approximately 1 in 100 patients undergoing total or partial knee replacement surgery and 1 in 200 patients undergoing total or partial hip replacement surgery will experience a venous thromboembolism event, including deep vein thrombosis and pulmonary embolism, before being discharged from the hospital, according to a new study.

Aspirin prophylaxis in people without prior cardiovascular disease does not appear to reduce cardiovascular death or cancer mortality, according to the results of a meta-analysis published online January 9 in the Archives of Internal Medicine.

FDA approved ingenol mebutate (Picato, LEO Pharma) gel (0.015%, 0.05%) for the topical treatment of actinic keratosis (AK). It is the first topical AK therapy that can be used for as few as 2 or 3 consecutive days.

Older women who use statins may be at an increased risk for diabetes mellitus, according to the results of a study published online January 9, in the Archives of Internal Medicine.

Baseline T score is the most useful way to determine how often to test bone mineral density (BMD) in older postmenopausal women with normal BMD or osteopenia at initial assessment, according to a study published in the New England Journal of Medicine (2012;366[3]:225-233).

Indian drug giant Ranbaxy has accepted a consent decree filed by the U.S. Department of Justice on behalf of FDA. The decree, which must still be accepted by the U.S. District Court for the District of Maryland, requires Ranbaxy to fix long-standing manufacturing problems at plants in India as well as a plant in the United States.

Approximately 1 in 100 patients undergoing total or partial knee replacement surgery and 1 in 200 patients undergoing total or partial hip replacement surgery will experience a venous thromboembolism event, including deep vein thrombosis and pulmonary embolism, before being discharged from the hospital, according to a study reported January 18 in the Journal of the American Medical Association.

Recently released study results suggest that rhinoplasty may make a patient look more than a year younger as well as improve his or her looks.

Certain characteristics of autism spectrum disorder (ASD) may change as a child ages. An analysis of a national survey of children’s health found that children with a current diagnosis of ASD were more likely to have a co-occurring neurodevelopmental or psychiatric condition, such as learning disability or depression, than those with a past (but not current) diagnosis of ASD. This is important information to have when arriving at an ASD diagnosis.

Indian drug giant Ranbaxy has accepted a consent decree filed by the U.S. Department of Justice on behalf of FDA. The decree, which must still be accepted by the U.S. District Court for the District of Maryland, requires Ranbaxy to fix long-standing manufacturing problems at plants in India as well as a plant in the United States.

FDA approved ingenol mebutate (Picato, LEO Pharma) gel (0.015%, 0.05%) for the topical treatment of actinic keratosis (AK). It is the first topical AK therapy that can be used for as few as 2 or 3 consecutive days.

Nearly one-fourth of U.S. adults say they would get plastic surgery if cost were not an issue.

The Endocrine Society recently released new clinical-practice guidelines recommending that all patients have their blood-glucose levels tested upon admission to the hospital, even if they haven’t had a prior diagnosis of diabetes.

Results of a survey of AAP members show that most US pediatricians bypass an ECG before starting children on stimulant medication for ADHD, opting for a routine cardiac history and physical examination instead. Find out how perceived barriers to cardiac screening influence clinical practice.

Welcome to the latest public health emergency: Shortages of anti-infective agents. These shortages can adversely affect clinical care and patient outcomes, according to a new study.

Half of teen mothers who became pregnant unintentionally say that they did nothing to prevent the pregnancy, according to data from a Centers for Disease Control and Prevention survey. The data show that misperceptions still abound regarding contraception and pregnancy, and it is never a bad idea to have frank talks with your patients—boys and girls alike.

Combined oral contraceptives (COCs) reduce menstrual pain in some women, a Swedish long-term study has found. Although COCs are commonly recommended to treat primary dysmenorrhea, a 2009 Cochrane Review called their efficacy into question.